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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of uveal melanoma (UM)
ncRNA name PVT1
ncRNA Category lncRNA
ID 5820
Ensembl ENSG00000249859
Synonyms LINC00079, MIR1204HG, NCRNA00079, onco-lncRNA-100
Disease name uveal melanoma (UM)
Species Homo sapiens
Tissues/Cell_line UM samples, skin melanoma samples
Methods RNA-seq
Expression pattern up-regulated
Functional description Results showed that high PVT1 expression group had a higher proportion of epithelioid cell dominant disease (a more malignant histological subtype than spindle cell dominant disease) and more cases of extrascleral extension (a risk factor for metastasis) compared with the low PVT1 expression group.
PubMed ID 29244840
Year 2017
Title High expression of lncRNA PVT1 independently predicts poor overall survival in patients with primary uveal melanoma.
Drug-related ncRNA NO

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